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Home > Early detection of colon cancer
Early detection of colon cancer

Price: 350 €

Turnaround time: 13 working days (monday to friday)

 

Over 25.000 cases of colorectal cancer are diagnosed in Spain every year, making it the second leading cause of cancer death and the most common cancer type in the developed world. Early detection of colorectal cancer means better response to treatment with survival rates of over 90% if the disease is detected in phase I. Colonoscopy is currently the most effective test although it represents a highly invasive screening method. Occult blood in stool is an accessible alternative but it needs strict sampling conditions and often leads to a high number of false positives. The new blood test overcomes these invasive or inaccurate screening methods.

 

TECHNIQUE FOR SEPT9 GENE DETECTION  

 

Echevarne Laboratory offers a new test aimed at the detection of the methylated form of the SETP9 gene in blood. Recent studies have found the methylated form of the Septin 9 gene (SEPT 9) in over 90 % of colorectal cancer patients. During neoplastic transformation the Septin9 gene is methylated in cells from the colorectal mucosa, and can be detected in DNA that is liberated into the blood stream from tumor cells. 

 

This test identifies tumors in their initial phase with a degree of specificity and sensitivity superior to any other method currently available (Phase I: 50%; Phase II and III: 75%; Phase IV: 98%).  A positive result implies presence of the marker in the patient’s plasma. A negative result in absence of clinical signs can be repeated every two years.

 

The protocol in Echevarne is fully automated from DNA extraction and warrants traceability and safety during the whole process.